Development of biomolecules with desired characteristics B-BMOL.028
Wykład (W) Semestr zimowy 2023/2024

Articles from the scientific journals recommended by the teacher.

KNOWLEDGE

W1. The student characterizes and explains the mechanisms of selected biotechnological processes and products obtained with their help (creation of

combinatorial libraries of peptides, peptidomimetics and aptamers; technologies of directed evolution: cell surface display, phage display, ribosome display, mRNA display, SNAP-tag display; selection of aptamers).

W2. The student describes the possibilities of using different organisms as sources of molecules used as patterns to obtain bioproducts with desired properties, e.g. peptides and proteins with antimicrobial and anticancer activity.

W3. The student characterizes the biotechnological potential of peptides, peptidomimetics and aptamers in the development of medicine, industry

and waste disposal.

SKILLS

U1. The student uses professional biotechnology terminology, describes and explains issues in the field of development of molecules with desired properties.

U2. The student assesses the risk related to the development of microbial resistance to antimicrobial peptides.

SOCIAL COMPETENCES

K1. The student is able to objectively assess his and other team members contribution to the work in solving specific tasks.

K2. The student is open to new trends in biotechnology.

A positive grade is given to a student who has obtained at least 50% of the maximum number of points.

Strategies for the development of new, biologically active peptides. Natural antimicrobial peptides (AMPs) as patterns for the development of highly active antimicrobial and antitumor molecules. Combinatorial libraries. Peptidomimetics. Directed evolution of peptides and proteins - technologies: phage display, ribosome display, mRNA display, SNAP-tag display. Aptamers – selection (SELEX techniques) and application.

informative lecture, discussion, multimedia presentation