Developmental biology
Informacje ogólne
Kod przedmiotu: | B-BM.074Eng |
Kod Erasmus / ISCED: | (brak danych) / (brak danych) |
Nazwa przedmiotu: | Developmental biology |
Jednostka: | Wydział Biologii i Biotechnologii |
Grupy: | |
Strona przedmiotu: | https://kampus.umcs.pl/course/view.php?id=10724 |
Punkty ECTS i inne: |
2.00
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Język prowadzenia: | angielski |
Wymagania wstępne: | Knowledge of zoology, anatomy and physiology of a high school program |
Godzinowe ekwiwalenty punktów ECTS: | Contact hours (with the participation of an academic teacher): Lecture 15 Laboratory 15 Non-contact hours (student's own work): Student's preparation for didactic classes: 10 Student's preparation for tests: 15 ECTS points: 2 |
Sposób weryfikacji efektów kształcenia: | On the basis of the UMCS Senate Resolution resolution No. XXII-39.6/12 of 25 April 2012, i.e. from the education cycle 2012/2013 Laboratory: written partial tests (W1-W3; U1, U2; K1, K3) oral presentation /activity during classes (W1-W3; U2-U4; K1-K3) Lecture: final test (W1-W3; U2; K1) participation in lectures (W1-W3; U2; K1) On the basis of the UMCS Senate Resolution resolution No. XXIV-27.18/19 of 29 May 2019, i.e. from the education cycle 2019/2020 Laboratory: written partial tests (W1-W3; U1; K1-K2) oral presentation /activity during classes (W1-W3; U1-U4; K-K2) Lecture: final test (W1-W3; U1; K1-K2) participation in lectures (W1-W3; U3-U2; K1-K2) |
Pełny opis: |
1. Female reproductive system 1 A. Ovary (structure, function) 1b. germ cells (origin, migration and colonization of genital ridge) 1c. oogenesis (mitosis, meiosis, oogonium, primary and secondary oocytes, ootid, polar bodies) 1d. ovary differentiation (gonadal/genital ridge consists of: coelomic epithelium, mesenchyme and primordial germ cells; primitive sex cords, secondary sex cords, egg nests, egg nest breakdown, medulla, cortex, type of follicles: primordial, primary, secondary, antral, preovulatory-Graafian follicle) 1e. the structure of Graafian follicle: secondary oocyte, zona pellucida, granulosa layer (estogen production), basement membrane, theca layer (externa, interna- steroidogenic cells (androgen production), corona radiata, cumulus oophorus, antrum. Two gonadotrophins and two cells theory. 1f. Atresia (follicular atresia, atretic follicles, apoptosis, fragmentation and lysis of oocyte, detachment of granulosa layer from basement membrane, loss of granulosa cell junctions Massive loss of oocyte during prenatal and postnatal female life. Recruitment, selection and dominance 1g. Ovulation (spontaneous, induced) 1h. corpus luteum (CL) formation, structure, function, and luteolysis 1B. Fallopian tube (uterine tube) – structure (simple columnar and ciliated epithelium, mucosal layer, muscularis layer and serosa ), function, origin (mesonephros, mesonephric duct (Wolffian), paramesonephric duct (Müllerian) 1C. Uterus – structure (morphological and histological, 3 layers- endometrium, myometrium and perimetrium, uterine glands, functonalis and basalis layers of endometrium) 1D. Menstrual cycle (proliferative phase, ovulation, luteal phase, menstruation), key hormones: FSH, LH, estrogens, progesterone (hormonal regulation of reproductive system- hypothalamus-pituitary-gonadal axis) 1E. Vagina (structure – stratified squamous epithelium, function), external genitalia (-only mention) 1F. Estrus cycle (proestrus, estrus, metestrus, diestrus, anestrus, the pattern of vaginal smears) – differences between menstrual and estrus cycle 1G. polyestrous, seasonally polyestrous (longer/shorter day breeders, diestrus, monoestrus animals, delayed fertilization and implantation. 2. Male reproductive system 2A. Testis (structure and function) 2b. Testis descent, cryptorchidism 2c. Testis lobules, seminiferous tubules 2d. The structure of seminiferous tubule (basement membrane, germ cells (spermatogonium, spermatocytes I, II, spermatids, spermatozoa, Sertoli cells) 2e. spermatogenesis (meiosis, spermatogonia Ad, Ap and B, spermatocytes I,II, spermatids, spermatozoa) 2f. spermiogenesis (spermatid – mature spermatozoa transformation) and spermatozoon structure (head, acrosomal cap, neck, middle piece, tail -flagellum) 2g. differences between oogenesis and spermatogenesis 2h. Sertoli and interstitial (Leydig) cells function 2i. testis differentiation (in fetus, SRY gen on Y chromosome- sex determination, TDF-testis determining factor, MIF- Müllerian inhibiting factor or anti-Müllerian hormone, Wolffian duct) 2j. Pathway of spermatozoa - Straight tubules - Rete testis - Efferent ductules - Epididymis (structure- stereocilia, sperm maturation) - Vas deferens (structure, function) - Ejaculatory duct - Urethra 2k. Accessory organs (structure and function) Seminal vesicles Prostate gland Bulbourethral glands Penis 2l. Hormonal regulation of the male reproductive system 3. Capacitation (Spermatozoa undergo the physiological changes to have the ability to fertilize an ovum). 4. Fertilization (acrosomal reaction, cortical reaction, polysperm block, fusion of male and female pronuclei -zygote) 5. Types of ova (alecithal, oligolecithal, mesolecithal, polylecithal, isolecithal and telolecithal, what is the yolk?) 6. Eggs or zygote polarity (animal, vegetal poles) 7. Cleavage (types, characteristic features, furrows: vertical, horizontal) 8. Blastula (structure, types: coeloblastula, discoblastula, stereoblastula, periblastula, blastocyst) 9. Gastrulation (definition, germ layers: ectoderm, mesoderm, endoderm, types of cell movement -invagination, involution, ingression, delamination, epiboly) 10. ecto, meso and endoderm differentiation into tissue 11. Zygotic induction or cytoplasmic inheritance as determinant of animal germ line 12. Embryonic induction (totipotent, pluripotent, multipotent stem cells, cell differentiation – gene activation and inhibition –acetylation, metylation) 13. Amphibian development - external or internal fertilization - frog egg organisation (animal, vegetal poles, cortex cytoplasm- dark, light and internal cytoplasm- grey, grey crescent - cleavage (holoblastic- complete cleavage, micromeres, macromeres) - structure of blastula (blastocoel, blastoderm) - gastrulation (blastopore, germ layers: ectoderm, mesoderm (grey crescent), endoderm), fate map of a frog embryo, way of gastrulation, gastrulation in detail (bottle cells, prechordal plate, chordamesoderm cells, notochord, ectoderm, endoderm, archenteron) - neurulation (neurula, ectoderm differentiation into: neural tube (in future brain and spinal cord), neural crest and epidermis) - mesoderm differentiation (paraxial mesoderm-somites, intermediate mesoderm- nephrotomes (gonads and urinary system), lateral mesoderm- splanchnic and somatic or vesceral and parietal mesoderm - organogenesis (primitive organs: notochord, neural tube, gut) - derivatives of germ layers 14. Bird development - chicken reproductive system - anatomy of an egg (polylecithal, telolecithal egg) - cleavage (meroblstic, discoidal, area pellucida, area opaca, blastodisc, blastoderm, epiblast, hipoblast, blastocoel, subgerminal space, Koller’s sickle region) - gastrulation (primitive streak, primitive knot=Hensen’s node, gastrulation in detail, germ cell layers, intraembrionic mesoderm, extraembrionic mesoderm) - ectoderm, mesoderm, endoderm differentiation (see amphibian development) - extraembrionic tissue (chorion, amnion, allantois, and yolk sac, function) - blood circulation in chicken embryo (three systems: vitelline- yolk sac, allantois and chicken circulation) 15. Mammals development -cleavage – the unique nature of mammalian cleavage - embryo compaction and cavitation (outer and inner cells) - blastula=blastocyst (embryoblast and trophoblast, blastocoel) - implantation (definition, phases) - placenta (trophoblast differentiation: syncytiotrophoblast, cytotrophoblast; placental formation, trophoblastic lacunae, primary, secondary and tertiary chorionic villi) - placenta structure and functions -umbilical cord - classification of placental types - gastrulation (germ disc, epiblast, hipoblast, primitive streak – see chicken development, amnioblast, amniotic cavity) - germ layer (ectoderm, mesoderm, endoderm differentiation – see amphibian development) - extraembryonic tissue, (chorion, amnion, allantois, and yolk sac, differences between chicken and human) - development of monozygotic twins |
Literatura: |
1. Sadler TW (2006) Langman's Medical Embryology, 10th edition. Wolters Kluwer/Lippincott Williams and Wilkins Company 2. Gilbert SF (2010) Developmental biology, 9th edition. Sinauer Associates. |
Efekty uczenia się: |
Based on the Resolution of the UMCS Senate No. XXII-39.6 / 12 of April 25, 2012, i.e. from the 2012/2013 education cycle: KNOWLEDGE W1. Understands the importance of sexual reproduction for biodiversity and evolutionary variability of organisms K_W02; K_W03 W2. Describes the stages of animal development - gametogenesis, fertilization, embryogenesis, organogenesis K_W05; K_W11 W3. Knows the mechanisms of reproduction, embryonic and fetal development of animals K_W01 SKILLS U1. Has an ability to use the light microscope K_U01 U2. Exhibits understanding of recommended academic textbooks K_U08 U3. Has an ability to prepare an oral presentation on specific developmental biology issues K_U17 U4. Uses biological terminology in scientific discussions K_U13 SOCIAL COMPETENCE K1. Adopts an active attitude towards acquisition, extension, and updating the acquired knowledge K_K03 K2. Has an ability to work in a team in order to solve problems, fulfil tasks efficiently and prepares presentation K_K08 K3. Analyses and evaluates contemporary problems and conflicts of ethical nature related to work with biological material K_K06 Based on the RESOLUTION of the UMCS Senate No. XXIV-27.18 / 19 of May 29, 2019. i.e. from the 2019/2020 education cycle: KNOWLEDGE W1. Understands the importance of sexual reproduction for biodiversity and evolutionary variability of organisms K_W05 W2. Knows and understands the various stages of animal development - gametogenesis, fertilization, embryogenesis, organogenesis K_W01 W3. Knows the mechanisms of reproduction, embryonic and fetal animal development K_W04 SKILLS U1. Has an ability to use the light microscope K_U04 U2. Has an ability to prepare an oral presentation on specific developmental biology issues K_U02; K_U03 U3. Can make a proper selection of data sources, conduct a critical analysis, evaluation and synthesis of information to solve problems and perform specific tasks K_U02 U4. Can communicate with the environment using specialist terminology in the field of developmental biology, participate in debates, adequately presenting and justifying the presented position and evaluating different opinions in a discussion K_U05 SOCIAL COMPETENCE K1. Adopts an active attitude towards acquisition, extension, and updating the acquired knowledge K_K02 K2. Is ready to perform occupational roles responsibly, e.g. to comply with the principles of professional ethics and require such compliance from other team members K_K05 |
Zajęcia w cyklu "Semestr zimowy 2022/2023" (zakończony)
Okres: | 2022-10-01 - 2023-02-01 |
Przejdź do planu
PN WT ŚR CZ PT |
Typ zajęć: |
Laboratorium, 15 godzin
Wykład, 15 godzin
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Koordynatorzy: | Monika Hułas-Stasiak | |
Prowadzący grup: | Monika Hułas-Stasiak | |
Lista studentów: | (nie masz dostępu) | |
Zaliczenie: |
Przedmiot -
Zaliczenie na ocenę
Laboratorium - Zaliczenie na ocenę Wykład - Zaliczenie na ocenę |
Właścicielem praw autorskich jest Uniwersytet Marii Curie-Skłodowskiej w Lublinie.